Pull the tearing notch and remove the neck seal before use.
Unscrew the cap and remove the plug. Replace the cap.
Remove protective shield covering the tip before using. Gently insert the nozzle tip into rectum with steady pressure with tip directed towards navel. Squeeze bottle until nearly all liquid is expelled. Now remove the tip from rectum. After squeezing, small quantity of liquid will remain in the bottle. It is not necessary to empty the bottle completely as bottle conatians a little extra to deliver the necessary dose easily. Maintain the body position till urge to evacuate is strong which takes about 2-5 minutes.